Medical Solutions

ANATech is launching a major R&D project to develop a non-invasive device for both clinics and home applications in response to the fast increasing problems details below. The unique knowledge base of ANATech founders combined with expert hematological labs, is expected to support a successful achievement of these objectives.

Non-Invasive Blood Glucose & Viscosity Measurement

The necessity for a compact, reliable and price affordable device for measuring glucose content in blood as well as blood viscosity cannot be understated. There are hundreds of millions of people around the world suffering from either of these two problems which require daily tracking and care, and which may deteriorate to se rious conditions if not cared-for on time. The daily tracking recommended by doctors is not exercised in most cases due to the inconvenience of present methods (for diabetes) and lack of compact usable device (for Hyperviscosity syndrome). The availability of a reliable affordable and compact meter, operating non-invasively, will open up a huge multi-billion dollar market world-wide.



General Background on Diabetes

Diabetics have suddenly increased in number due to reduced physical activities and changes of eating habits. In the US, diabetes affects 25.8 million people of all ages, which are 8.3% of the U.S. population. Only 18.8 million of these are diagnosed. As of 2010 an estimated 79 million American adults ages 20 years or older have pre-diabetes. Diabetes is the leading cause of kidney failure, nontraumatic lower-limb amputations, and new cases of blindness among adults in the United States. It is also a major cause of heart disease and stroke.
Diabetes is responsible for 11.6% of deaths among 20 to 79-year-olds in England. “Diabetes UK” says in most cases the disease kills indirectly by leading to strokes, heart attacks or kidney failure. It is often not recorded on death certificates, which is why the number of deaths attributable to diabetes has consistently been underestimated. If current trends persist one in eight deaths in the same age group would be attributable to diabetes by 2010.

Overall, the risk for death among people with diabetes is about twice that of people of similar age but without diabetes.

Self-monitoring of blood glucose is an important component of modern therapy for diabetes and offers information about blood glucose levels at many times points to enable main­tenance of a more constant glucose levels in everyday life. The self-monitoring of blood glucose is suggested to be taken at least three or four times a day. Periodical tests by the invasive method cause pain and discomfort during blood-taking, and also impose mental and economic burdens with considerable costs of consumable accessories necessary for blood-taking (not to mention the hygienic aspect).


General Background on Blood Viscosity

Plasma and serum viscosity measurements have an important role in the clinical management of patients prone to hyperviscosity syndrome (HVS). Hyperviscosity syndrome can occur in association with a variety of clinical diagnoses, such as polycythemia, Waldenström macroglobulinemia, multiple myeloma, and leukemia.

Overly thick blood can potentially clot in the patient's veins, leading to health problems. High blood viscosity also forces the heart to work harder to pump the blood, increasing the risk that a patient's heart will give out.
High blood viscosity invariably accompanies degenerative diseases.
Confusion and mental status changes result from the increased viscosity of the blood and decreased cerebral blood flow. This sludging leads to segmental dilatation of retinal veins and retinal hemorrhages. Mucosal bleeding may occur from prolonged bleeding time caused by myeloma proteins interfering with platelet function.
Cardiopulmonary symptoms such as shortness of breath, hypoxemia, acute respiratory failure, and hypotension also result from this sludging of blood and decreased micro vascular circulation.
Clinical sequelae of HVS can include congestive heart failure, ischemic acute tubular necrosis, and pulmonary edema with multi organ system failure and death if treatment is not promptly initiated. Thus, prompt recognition and expeditious treatment are imperative in preventing deterioration

Clinical laboratory professionals must choose among instruments that are not intended primarily for clinical laboratory use but are adaptable from industrial applications, with proper validation.
The resulting conclusion from all the above detailed is that there is a real need in the market for reliable blood viscosity meter in both labs and general use - similar to the home-blood pressure meter.